Choices are a huge part of our lives. That must be true for characters in novels, too. Each and every character you write will be faced with choices, and some of them are going to be the wrong choices. As someone who hates making mistakes, I cringe when my characters do something they shouldn't. Or don't do something that they should.
But I still make them do it. Why? Because that leads to conflict! And conflict is what leads to a great story. Consequences are another fact of life, and in a novel, the consequences your protagonist suffers should be extreme. And they should CHANGE that character so that they don't do it again.
That is key! Human beings fail to learn from their mistakes over and over again, but when a character in a book fails to learn anything from their mistakes, we grow weary with them. And sometimes they even make us mad.
Just because mistakes make us cringe, though, it doesn't mean that we should avoid them. And we CERTAINLY shouldn't avoid making choices. So go find a situation where your protagonist, antagonist, or even a secondary character can make a big choice that makes the "situation" worse! Then make those characters work to solve it.